Clinically Tested Results.

Natural, non-pharmaceutical ingredients working together.

In 2004, we had plenty of anecdotal evidence our formula, Syntra5, helped patients maintain healthy blood sugar levels. We began pursuing clinical testing on our formula to support what we’d observed. From that first study, we learned that it not only supported stable blood glucose, but also helped maintain healthy cholesterol, triglyceride, and blood pressure levels. Subsequent studies have shown Syntra5 to be a first choice for those seeking non- pharmaceutical options.

The Gold Standard.

The “gold standard” of clinical pharmaceutical research is and continues to be what’s called a placebo-controlled, randomized double-blind study. But what does that mean?

You may have heard the word “placebo” used alternately with “sugar pill”. What both terms mean is simply that the substance is not active and should do nothing, while the active substance does (or doesn’t do) what it’s suspected to do. The person taking it doesn’t know which one they’re getting. Another term you probably know, the “placebo effect”, is where a product works because a researcher or participant believes in the product, and may not be reporting their objective experience. “Randomized” means just that: random. In a study, some patients are given the placebo, and some are given the “active” subject of the test (in our case, Syntra5) without any other qualifications.

In order to avoid bias from researchers or participants, a randomized study doesn’t follow a pattern administering either pill. The unpredictability helps keep the test objective.

And when we call a researcher or subject “blind,” we just mean that person doesn’t know who is receiving an active medication and who’s receiving a placebo. You’ve heard the term “single-blind,” which means the subject doesn’t know which one they’re taking. In a double-blind study, you guessed it: neither the researcher nor the subject know if they’re taking a placebo or an active. Double-blind studies help eliminate biases and the “placebo effect” .

And why is this important? Dietary supplements are subject to different regulations, and therefore do not usually have a reason to undergo double-blind testing. As a dietary supplement, Syntra5 is unique in that it has undergone this more rigorous testing.

The Scope & Study.

Our clinical testing of Syntra5 studied 100 subjects (47 men and 53 women) with fasting blood glucose levels between 160 and 240 mg/dL. The participants were randomly assigned either six oral Syntra5 tablets daily or a placebo for 90 days. We measured fasting blood glucose, body mass, oral glucose tolerance test, total cholesterol, HDL, triglycerides, blood pressure, and other markers at both baseline and at the study’s conclusion.

The Formula.

How did we pick our ingredients?

We chose the ingredients in the original formulation for Syntra5 in 1999 with the help of a respected Seattle-based bariatric physician – himself a person with unhealthy blood sugar. At that time, we only included three ingredients. We chose them based on strong evidence that they were effective in promoting healthy blood sugar: hydroxycitric acid (HCA), chromium, and vanadium. These are still the ingredients at the heart of Syntra5.

HCA was and is still the superstar of Syntra5. It’s derived from the tropical tree fruit Garcinia Cambogia, and works in three specific ways: it increases the body’s sensitivity to insulin, converts more blood sugar to fuel, and suppresses appetite better than any other natural compound ever tested.

Chromium, meanwhile, has been shown to help insulin work better in the body and fight insulin resistance. Vanadium both increases insulin sensitivity and actually mimics insulin’s catalyst action in the body.

We continued working on the formula between 1999 and 2004, as more clinical research became available on various vitamins, minerals, and herbal extracts. Our goal has always been to produce an effective formula, and we chose these ingredients carefully based on outside individual clinical research. New studies on vitamin c, biotin, gymnema sylvestre, cinnamon, bitter melon, banaba, and fenugreek made them important elements in the formula.

See For Yourself

Review the results of our two studies.

Human Double-Blind Study
Murine Study

Syntra5

Blood Sugar Support

Syntra5 is the most studied and clinically tested dietary supplement in its category, and has been shown to be a superior choice in promoting numerous health markers. Combining supplements like HCA, chromium, vanadium, gymnema sylvestre, cinnamon, bitter melon, banaba, and fenugreek makes Syntra5 an all-natural alternative to costly, side-effect-laden pharmaceuticals.

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